TSH (Thyroid Stimulating Hormone)
TSH (Thyroid Stimulating Hormone) is produced by the pituitary gland to control thyroid function. The thyroid gland acts like your body's metabolic thermostat — controlling energy production, heart rate, body temperature, weight, and mood. Almost every cell in the body has thyroid hormone receptors. The Vsense TSH estimate is derived from physiological patterns — clinical blood testing gives precise values.
Normal range
How Vsense measures it
Vsense estimates thyroid function from physiological patterns — resting heart rate, HRV patterns, temperature-related vascular signals, and metabolic markers. A blood test for TSH, free T3, and free T4 gives the definitive clinical picture.
How it's scored
Normal TSH: 0.4–4.0 mIU/L. Many functional medicine practitioners consider 1.0–2.5 mIU/L optimal. High TSH suggests underactive thyroid (hypothyroidism). Low TSH suggests overactive thyroid (hyperthyroidism).
What a high reading means
High TSH means the pituitary is 'shouting' to a sluggish thyroid — indicating hypothyroidism. Symptoms: persistent fatigue, unexplained weight gain, cold intolerance, constipation, brain fog, depression, dry skin, hair loss, slow heart rate, and high cholesterol. Hashimoto's thyroiditis (autoimmune) is the most common cause in adults.
What a low reading means
Low TSH means the thyroid is overactive (hyperthyroidism). Symptoms: weight loss despite good appetite, rapid heartbeat (palpitations), heat intolerance, tremor, anxiety, insomnia, and frequent bowel movements. Graves' disease is the most common cause. Both conditions require medical evaluation and are very treatable.
How to improve it
Exercise
- Regular moderate exercise supports thyroid health and metabolism
- Avoid extreme overtraining — it can suppress thyroid function through cortisol elevation
- For hypothyroid: start gently and build gradually — fatigue is common at the start
Diet
- Selenium-rich foods (Brazil nuts — just 2/day covers your needs, shellfish, eggs) are critical for thyroid hormone conversion from T4 to active T3
- Iodine from seaweed, fish, and dairy supports thyroid hormone production — but avoid excessive supplementation
- Avoid raw cruciferous vegetables in excess if hypothyroid — cooking deactivates goitrogenic compounds
- Zinc (oysters, red meat, pumpkin seeds) supports thyroid enzyme function
- Avoid gluten if you have Hashimoto's — molecular mimicry between gluten and thyroid tissue is well documented
Lifestyle
- Avoid toxin exposure — heavy metals (mercury, fluoride) and endocrine disruptors (BPA, phthalates) harm thyroid function
- Manage stress — cortisol directly suppresses thyroid hormone production and T4-to-T3 conversion
- Get adequate sleep — thyroid hormone is mainly secreted during sleep
- Get regular thyroid testing if you have family history or symptoms — TSH is a simple blood test
Natural remedies
- Selenium supplementation (200mcg/day) reduces thyroid antibodies in Hashimoto's thyroiditis within 3 months
- Myo-inositol (2–4g/day) combined with selenium reduces Hashimoto's antibodies in clinical studies
- Ashwagandha root supports thyroid hormone levels in subclinical hypothyroidism
- Vitamin D (2,000–4,000 IU/day) reduces thyroid autoantibodies — deficiency is extremely common in Hashimoto's
Frequently asked questions
Should I get my thyroid tested?
If you have persistent fatigue, unexplained weight changes, hair loss, cold intolerance, or depression, a TSH blood test is a sensible first step. It's a simple, affordable blood test that screens for both over- and under-active thyroid.
What's the difference between T3, T4, and TSH?
TSH is released by the pituitary gland to stimulate the thyroid. The thyroid produces T4 (inactive) and T3 (active). T4 is converted to T3 in tissues. Most people test TSH first; adding free T3 and free T4 gives a fuller picture of thyroid function.
Can stress cause thyroid problems?
Chronic stress directly suppresses thyroid function via cortisol. Stress also dysregulates the immune system, which can trigger autoimmune thyroid conditions (Hashimoto's or Graves'). Managing stress is important for thyroid health.
Can thyroid issues cause depression?
Yes — hypothyroidism is a common and underdiagnosed cause of depression. Thyroid hormone is essential for neurotransmitter production and brain metabolism. Many people diagnosed with depression improve dramatically once a hypothyroid condition is treated.
Is hypothyroidism permanent?
Hashimoto's is typically permanent and requires thyroid hormone replacement long-term. However, some subclinical hypothyroidism cases resolve with addressing root causes (selenium deficiency, gluten, stress, vitamin D). Hyperthyroidism from Graves' disease can go into remission with treatment.

